Publications

Adducins inhibit lung cancer cell migration through mechanisms involving regulation of cell-matrix adhesion and cadherin-11 expression

Cell migration is a critical mechanism controlling tissue morphogenesis, epithelial wound healing and tumor metastasis. Migrating cells …

The Rate of Change in Alcohol Misuse Across Adolescence is Heritable

BACKGROUND: Alcohol use typically begins during adolescence and escalates into young adulthood. This represents an important period for …

Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains

Genetic differences in acute behavioral responses to ethanol contribute to the susceptibility to alcohol use disorder and the reduction …

Establishing an analytic pipeline for genome-wide DNA methylation

The need for research investigating DNA methylation (DNAm) in clinical studies has increased, leading to the evolution of new analytic …

Integrating Genomic and Genetic Data Across Species to Identify Gene Networks Contributing to Ethanol Behaviors and Alcohol Use Disorder

Mouse genomic studies on acute or chronic ethanol exposure models have been previously used to identify gene networks and cognate hub …

Incorporating Bioinformatics Data to Understand Alcohol-related GWAS Results

PURPOSE. Genome-wide association studies (GWAS) of alcohol dependence and genetically correlated externalizing disorders have produced …

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small …

Integrating genomic and genetic data suggests circuit development abnormalities in schizophrenia

It seems likely that the genetic contribution of common variants to the risk of major psychiatric disorders is distributed across at …

Role of Adrenal Glucocorticoid Signaling in Prefrontal Cortex Gene Expression and Acute Behavioral Responses to Ethanol

BACKGROUND: Glucocorticoid hormones modulate acute and chronic behavioral and molecular responses to drugs of abuse including …

Identifying Gene Networks Underlying the Neurobiology of Ethanol and Alcoholism

For complex disorders such as alcoholism, identifying the genes linked to these diseases and their specific roles is difficult. …

MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA

Despite the advances in immunosuppression, renal allograft attrition over time remains unabated due to chronic allograft dysfunction …

Urine miRNA panel as accurate biomarkers for monitoring kidney graft function

Background. Improvement in short term outcomes in kidney transplantation (Tx) had been achieved. However, long-term outcomes have not …

Using expression genetics to study the neurobiology of ethanol and alcoholism

Recent simultaneous progress in human and animal model genetics and the advent of microarray whole genome expression profiling have …

The benefits of human-companion animal interaction: a review

This article provides a review of research published since 1980 on the benefits of human-companion animal interaction. Studies focusing …