Article-Journal

osfr: An R Interface to the Open Science Framework
An R interface to the Open Science Framework.
Aaron R Wolen, Chris Hartgerink, Ryan Hafen, Brian Richards, Courtney K Soderberg, Timothy P York
PDF Cite Code Project DOI
Adducins inhibit lung cancer cell migration through mechanisms involving regulation of cell-matrix adhesion and cadherin-11 expression
Cell migration is a critical mechanism controlling tissue morphogenesis, epithelial wound healing and tumor metastasis. Migrating cells …
Susana Lechuga, Parth H Amin, Aaron R Wolen, Andrei I Ivanov
Cite DOI
Cross-species alcohol dependence-associated gene networks: Co-analysis of mouse brain gene expression and human genome-wide association data
Genome-wide association studies on alcohol dependence, by themselves, have yet to account for the estimated heritability of the …
Kristin M Mignogna, Silviu a Bacanu, Brien P Riley, Aaron R Wolen, Michael F Miles
Cite DOI
Incorporating Functional Genomic Information to Enhance Polygenic Signal and Identify Variants Involved in Gene-by-Environment Interaction for Young Adult Alcohol Problems
BACKGROUND: Characterizing aggregate genetic risk for alcohol misuse and identifying variants involved in gene-by-environment (G × E) …
Jessica E Salvatore, Jeanne E Savage, Peter Barr, Aaron R Wolen, Fazil Aliev, Eero Vuoksimaa, Antti Latvala, Lea Pulkkinen, Richard J Rose, Jaakko Kaprio, Danielle M Dick
Cite DOI
The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort
The transition from acute to chronic ethanol exposure leads to lasting behavioral and physiological changes such as increased …
Andrew D Van Der Vaart, Jennifer T Wolstenholme, Maren L Smith, Guy M Harris, Marcelo F Lopez, Aaron R Wolen, Howard C Becker, Robert W Williams, Michael F Miles
PDF Cite DOI
Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students
Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. …
Bradley T Webb, Alexis C Edwards, Aaron R Wolen, Jessica E Salvatore, Fazil Aliev, Brien P Riley, Cuie Sun, Vernell S Williamson, James N Kitchens, Kimberly Pedersen, Amy Adkins, Megan E Cooke, Jeanne E Savage, Zoe Neale, Seung B Cho, Danielle M Dick, Kenneth S Kendler
PDF Cite DOI
The Rate of Change in Alcohol Misuse Across Adolescence is Heritable
BACKGROUND: Alcohol use typically begins during adolescence and escalates into young adulthood. This represents an important period for …
Alexis C Edwards, Jon Heron, Vladimir Vladimirov, Aaron R Wolen, Daniel E Adkins, Fazil Aliev, Matthew Hickman, Kenneth S Kendler
PDF Cite DOI
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans
The bioactive sphingolipid sphingosine-1-phosphate (S1P) and the kinase that produces it have been implicated in inflammatory bowel …
Wei-Ching Huang, Jie Liang, Masayuki Nagahashi, Dorit Avni, Akimitsu Yamada, Michael Maceyka, Aaron R Wolen, Tomasz Kordula, Sheldon Milstien, Kazuaki Takabe, Tamas Oravecz, Sarah Spiegel
PDF Cite DOI
Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains
Genetic differences in acute behavioral responses to ethanol contribute to the susceptibility to alcohol use disorder and the reduction …
A H Putman, A R Wolen, J L Harenza, R K Yordanova, B T Webb, E J Chesler, M F Miles
PDF Cite DOI
Establishing an analytic pipeline for genome-wide DNA methylation
The need for research investigating DNA methylation (DNAm) in clinical studies has increased, leading to the evolution of new analytic …
Michelle L Wright, Mikhail G Dozmorov, Aaron R Wolen, Colleen Jackson-Cook, Angela R Starkweather, Debra E Lyon, Timothy P York
PDF Cite DOI